• Lupus (Systemic Lupus Erythematosus): A chronic condition causing joint pain, fatigue, a butterfly-shaped facial rash, and organ inflammation.

• Rheumatoid Arthritis (RA): An inflammatory disorder that leads to painful swelling and stiffness in the joints.

• Hashimoto's Thyroiditis: An underactive thyroid condition causing fatigue, cold sensitivity, and weight gain.

• Graves' Disease: An overactive thyroid condition leading to rapid heartbeat, weight loss, and anxiety.

• Multiple Sclerosis (MS): A central nervous system disease where the immune system attacks the protective lining of nerves. 

Common Symptoms to Watch For

• Persistent, overwhelming fatigue

• Joint and muscle pain, stiffness, or swelling

• Skin rashes or sensitivity to sunlight

• Unexplained weight fluctuations or low-grade fevers

• Digestive issues or stomach pain 

Why Women Are at Higher Risk

• Genetics and X Chromosomes: Females have two X chromosomes, which contain a high concentration of genes tied to immune function. A molecule called Xist, which deactivates one of the X chromosomes, can sometimes trigger overactive immune responses. 

• Hormones: Sex hormones like estrogen and progesterone heavily influence and strengthen immune activity, which can tip the balance toward overactivity and inflammation.